Mood disorders: Modelling and managing complexity

Managing mood disorders and comorbid personality disorders.

PURPOSE OF REVIEW To examine the influence of personality disorder comorbidity on the general treatment of mood disorders. RECENT FINDINGS Personality disorders generally have a negative influence on outcome of mood disorders, both unipolar and bipolar. When the personality features are addressed, however, the outcome is less negative. Recent studies suggest a special role for psychological a...

Diagnosing and managing psychotic and mood disorders.

Managing Variability Complexity in Aspect Oriented Modelling

Aspect-Oriented Modeling (AOM) approaches propose to model reusable aspects that can be composed in different systems at a model level. To improve the reusability, several contributions have pointed out the needs of variability in the AOM approaches. Nevertheless, the support of variability makes more complex the aspect design and the introduction of several dimensions of variability (advice, p...

Managing mood disorders in patients attending pulmonary rehabilitation clinics

BACKGROUND There is good evidence for the positive benefits of pulmonary rehabilitation (PR) in the prevention of hospital admissions, lower mortality, and improved health-related quality of life. There is also increasing evidence about the impact of PR on mental health and, in particular, mood disorders. We aimed to identify how depression in chronic obstructive pulmonary disease (COPD) patien...

The ups and downs of modelling mood disorders in rodents.

The wide spectrum of disruptions that characterizes major depressive disorder (MDD) and bipolar disorder (BD) highlights the difficulties researchers are posed with as they try to mimic these disorders in the laboratory. Nonetheless, numerous attempts have been made to create rodent models of mood disorders or at least models of the symptoms of MDD and BD. Present antidepressants are all descen...